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JiaoGulan Aum MiracleTea gift pack (30g)

Name: JiaoGulan Aum MiracleTea gift pack (30g)
SKU: 530
Price: 11.11 EUR
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€11.11

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Jiaogulan is a herb from my native southern China that I believe possesses the most wide-ranging benefits for human health and wellness of any plant yet discovered.

This may seem like a bold statement, but having studied this remarkable tonic herb for more than twenty years, I can assure you that there is strong scientific support to back up my passion for jiaogulan – Dr. Jialiu Liu, ‘Father of Jiaogulan’

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Categories: Broad Spectrum, Cancer focused, Rare Supplements, Skin Nutrition, Weight Management Tags: adaptogen, anti proliferative, antioxidant, balancing, blood, calming, CFS, energy, Heart, jiaogulan, kidneys, liver, nerve tonic, nitric oxide regulator, protective, skin, SOD, stimulating, stree, tea

Description

Description

What is Jiaogulan?

Praised as “The Herb of Immortality” in China, Jiaogulan (Gynostemma pentaphyllum) is a climbing vine of the cucumber/gourd family, believed to contribute to a long and disease-free life due to its powerful anti-aging effects and possibly the widest spectrum of health benefits of any plant known to science.

Jiaogulan is a herb from my native southern China that I believe possesses the most wide-ranging benefits for human health and wellness of any plant yet discovered. This may seem like a bold statement, but having studied this remarkable tonic herb for more than twenty years, I can assure you that there is strong scientific support to back up my passion for jiaogulan.Dr. Jialiu Liu, ‘Father of Jiaogulan’

“After many years studying hundreds of herbs, we ultimately came to the realization that Jiaogulan was not only the rainforest’s most precious gift, but was in fact nature’s greatest treasure. We began to use Jiaogulan in our medical university hospital with great success for a wide variety of conditions, and before long, it was also being used at numerous other hospitals throughout China.”Dr. Jialiu Liu, ‘Father of Jiaogulan’

Jiaogulan the Adaptogen

Adaptogens are rare and remarkable plants that increase the body’s ability to counter and resist physical, chemical, biological, emotional, and environmental stressors by raising nonspecific resistance toward such stress. They decrease the organism’s susceptibility to illness by allowing it to “adapt” to the stressful circumstances.

Adaptogens support normal metabolism, help restore balance to the immune, nervous, and endocrine systems, and allow the body to maintain optimal homeostasis. They usually also benefit the liver, cardiovascular system, kidneys, and pancreas.

For a plant to be qualified as an adaptogen, it must meet the following 3 criteria as defined by Israel I. Berkhman, PhD, and Dr. I. V. Dardymov in 1968:

Nontoxic
An adaptogen is nontoxic to the recipient. It must cause minimal side effects on physical or mental health.

Increases Resistance to Stress
An adaptogen produces a nonspecific response in the body—an increase in the power of resistance against multiple stressors including physical, chemical, or biological agents in multiple nonspecific ways, including the building of a reserve of “adaptive energy”. This reserve is then used when an actual stressor arises, instead of depleting the cells of vital energy.

Has a Normalizing Effect
An adaptogen is “intelligent” in that it has a normalizing influence on physiology, regardless of the direction of change from the normal state caused by the stressor. This normalizing influence implies the capability of adaptogens for a bidirectional effect on physiological function. They are capable of either toning down or strengthening the activity of multiple systems, including the neuro-endocrine and immune systems, depending on the need. For example, if a person with high blood pressure is given Jiaogulan, their blood pressure will drop. If on the other hand their blood pressure is below normal, it will raise.

Some of these triterpenoid saponins have been identified as having adaptogenic properties, while others were found to have anti-inflammatory, hepatoprotective (protecting the liver), adrenal gland strengthening, and immune system modulating effects.²
Jiaogulan is a premier adaptogen, and has been described as “Like Ginseng, but better than Ginseng” because of the energizing effect both plants have on the body.

However, while Ginseng is often poorly tolerated and can cause insomnia, tachycardia and nervousness, Jiaogulan has the opposite effects because it is a superior adaptogen.

Jiaogulan the Supreme Antioxidant

Jiaogulan contains some of the rarest and most powerful antioxidant properties.It stimulates the body’s own production of Superoxide Dismutase (SOD), Glutathione, and Catalase, the 3 most important endogenous (produced by the organism) antioxidants that help your body fight against free radicals – the cause of aging and a myriad of diseases.

For years, scientists have sought ways to boost the body’s most powerful internal antioxidants: Superoxide Dismutase (SOD) and Glutathione.

Until now, no natural and effective ways of boosting SOD levels had been discovered.

Glutathione is the other vitally important endogenous antioxidant, produced within each and every cell of your body. It prevents cell damage by neutralizing free radicals and maintains dietary antioxidants such as vitamins C and E in their active forms so that they can keep fighting free radicals.

It also plays a critical and integral part in detoxifying the body by binding to pesticides, heavy metals and other toxins until they are excreted, it regulates protein and DNA synthesis and cell growth, and is critical in helping your immune system perform its role of fighting infections and preventing cancer.

Lastly, glutathione helps us reach peak mental and physical function by decreasing muscle damage, reducing recovery time, increasing strength and endurance, and shifting metabolism from fat production to muscle development.

SOD-Lifespan2

Cutler’s cross-species investigations strongly suggest that SOD is a primary determinant of longevity in mammals, and that increased SOD production plays a key role in the higher order of mammals’ evolution from shorter to longer life spans.

Jiaogulan Promotes Youth and Longevity by Stimulating SOD and Glutathione Production

Jiaogulan’s remarkable ability to stimulate the body’s own production of both SOD and glutathione must be at the heart of the reason why it has been so strongly associated with anti-aging and longevity.Science has finally found the mechanism to explain how and why so many Jiaogulan users in China lived to be 100 years old in good health, and why they called it “The Herb of Immortality”.

The stimulation of SOD and glutathione production may also be greatly responsible for the preventive and therapeutic qualities the herb has.

The older you are the better!!
A Guiyang Medical College human clinical trial with 610 healthy middle and advanced age patients, aged 50 to 90, showed that SOD levels returned to their youthful levels after only one month of daily intake of 20 mg of gypenosides (the main active ingredients in Jiaogulan)!

Those between 70 and 90 years of age saw an average decrease in the harmful superoxide and other radicals of 21.4% and an average increase in internally produced SOD of 282.8%, while in the 50 to 69 age group there was a 15.6% decrease in oxidant levels and a 116.1% increase in SOD concentrations! A control group not receiving gypenosides from Jiaogulan did not experience any change.²²

In another 2-month double-blind experiment at the Shanghai Institute of Geriatrics, 51 elderly patients were administered 60mg of Jiaogulan gypenosides daily for 2 months, while a control group of 40 patients were given a placebo. This study too found a significant increase in SOD levels and significant decrease in cell damage from oxidation. In addition, the researchers saw an improvement in the memory of the patients. None of these effects were observed in the placebo group.²⁵

In addition to these landmark human studies, there have been many animal and in-vitro studies that have demonstrated the protective effects Jiaogulan has on the body’s cardiovascular^{21, 26, 27, 28, 29, 31}, immune^{26, 32}, nervous^{31, 33, 34, 35 36,37, 38, 49}, and reproductive³⁹ systems and various organs, such as the liver^{26, 40, 41, 42, 43, 44, 45}, kidneys^{29, 31}, stomach⁴⁶, and skin^{47, 48}, due to its ability to boost the organism’s own defenses against free radicals by stimulating the production of SOD, Glutathione ^{31, 35, 37, 43, 44, 50, 51, 52}, and Catalase^{44, 48, 50, 51}.

This boost of endogenous antioxidants was also found to have anti-inflammatory^{29, 53}, anti-cancer ^{53, 54} and anti-aging ^{32, 47, 48, 55, 56} effects, and to be beneficial for athletic performance and faster recovery from exercise⁵¹.

Jiaogulan as a Nitric Oxide Regulator

nitric oxide and body system benefits
Nitric Oxide (NO) is a gas and free radical produced in the body that is deemed so important in human physiology that it was named “Molecule of the Year” by the journal Science in 1992.⁵⁸Few people realize it, but Nitric Oxide is probably the most important chemical compound for cardiovascular health.

The President of the American Heart Association called it “the most important discovery in the history of cardiovascular medicine”, and in 1998, the Nobel Prize for Medicine was given to the three scientists who discovered the role of Nitric Oxide as a cardiovascular signalling molecule.

Simply put, adequate Nitric Oxide production is the first step in a chain reaction that promotes healthy cardiovascular function, while insufficient production triggers a cascade of destruction that eventually results in heart disease.

However, Nitric Oxide concentrations that are too low or too high can result in a number of serious conditions and diseases like heart disease, stroke, cognitive decline, Alzheimer’s, Parkinson’s, autoimmune diseases, chronic inflammation, rheumatoid arthritis, gout, and many more.

Studies have now shown that Jiaogulan has the remarkable ability to both protect and stimulate the production of Nitric Oxide (NO) when your body produces too little of it^{6, 57, 59, 60, 61}, or to limit its production when it is out of control^{38, 62, 63, 64}.

Since diseases arise when Nitric Oxide levels are either too high or too low, the regulatory effect of Jiaogulan on its production is crucial in maintaining good health through balance, and is further testament to the herb’s adaptogenic properties.

Jiaogulan Promotes Cardiovascular Health

Heart and blood vessel disease is the #1 cause of death in the world, resulting in 17.3 million annual deaths globally. In the United States it killed almost 800,000 people in 2013 alone.The majority of problems classified under the umbrella of heart disease are related to a process called atherosclerosis, or thickening and hardening of the arteries.

Jiaogulan prevents damage to the arterial lining in two ways:

First, it neutralizes the oxidative damage to the arteries caused by free radicals and cholesterol through its powerful antioxidant effects^{26, 27, 29} (see Antioxidant section).

The second way Gynostemma prevents endothelial damage is through its ability to regulate blood pressure, either lowering it ^{63, 65} or elevating it ⁶³ depending on the need.

The herb’s ability to lower blood pressure is at least in part due to its protection and stimulation of endothelial Nitric Oxide production.^{6, 57, 59, 60}

One double blind clinical study of patients with high blood pressure showed that Jiaogulan is almost as effective as Indapamide (a high blood pressure drug), and almost twice as effective as Panax Ginseng (82%, 93%, and 46% respectively) in reducing high blood pressure.⁶⁵

Jiaogulan has demonstrated its ability to lower bad cholesterol (LDL) and triglyceride levels, while raising good cholesterol (HDL) levels in a number of studies.^{18, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84}

It achieves this by improving the body’s ability to metabolize fat and by stimulating Nitric Oxide production, which suppresses the damage done to bad (LDL) cholesterol by free radicals.

Jiaogulan Prevents Platelet Stickiness and Blood Clots

Plaques grow over years and slowly blocks blood flow in the arteries. What’s worse, cholesterol plaque can suddenly rupture, especially where the person suffers from high blood pressure.When a plaque inside a coronary artery ruptures, platelets (blood cells whose function is to stop the bleeding) become sticky, develop tentacles and start to roam around in gangs (platelet aggregation) and quickly make their way to the damaged area and pile on it until they either partially or completely block the artery.

Jiaogulan reduces the affected area and the severity of injury to the brain and heart suffered as a consequence of a stroke or a heart attack, and accelerates the healing and recovery process.^{95, 96, 97, 98}

The herb prevents heart muscle disease (cardiomyopathy) and protects heart muscles and their function from damage as a result of diabetes.^{99, 100}

Jiaogulan also helps protect against coronary spasms, irregular heartbeat (arrhythmia), pressor response (the increase in arterial blood pressure in response to various internal or external conditions, e.g. drugs, mental stress, etc.), and ventricular tachycardia (a life-threatening rapid heart beat that starts in the bottom pumping chambers of the heart).¹⁰¹

Jiaogulan is beneficial for people who suffer from congestive heart failure because it improves the efficiency of the pumping action of the heart. This means the heart does not work as hard to produce the same amount of blood flow, helping it deliver more oxygen and nutrients to the body as a whole without causing additional stress. ^{102, 103}

Jiaogulan and Cancer

Research has shown that Jiaogulan has many cancer fighting and prevention effects on a wide variety of cancers.

It works on several levels to prevent and heal cancer:

•It enhances the body’s own defences by protecting and boosting the immune system. A strong immune system is important for preventing the formation of tumours.

•With its exceptional antioxidant effects, Jiaogulan scavenges free radicals within the body, minimizing DNA mutations that lead to tumours. (See the Antioxidant section for more information)

•Its chemical components like saponins (gypenosides), flavonoids and polysaccharides have direct anticancer action.

Jiaogulan has been shown in studies to reduce tumour size, inhibit tumour growth and metastasis (spreading), cause apoptosis (tumour cell death) by increasing free-radical damage to cancer cells, and inhibit energy production in cancer cells.

These effects have been demonstrated in several types of cancer, including:

Liver (hepatoma)^{104, 105, 106, 107, 108, 109, 110, 111, 112, 113}
Lung^{114, 115, 116, 117, 118, 119, 120}
Prostate¹²¹
Colorectal^{122, 123, 124, 125}
Esophageal ^{122, 126}
Oral^{127, 128, 129, 130, 131, 132, 133, 134, 135}
Brain¹³⁶
Stomach ^{137, 138}
Skin (melanoma)^{139, 140}
Uterus/cervix^{141, 142, 143}
Leukaemia^{144, 145, 146, 147}
Sarcoma ^{147, 148}

For those who choose to use the traditional methods of cancer treatment – chemotherapy and radiation therapy – Jiaogulan has shown to be an invaluable ally.

This is because it provides a very strong protection against the damaging effects these treatments have on the immune system.^{149, 150, 151, 152, 153, 154}

Jiaogulan was also found to diminish the overall damaging effects of drug toxicity from chemotherapy^{137, 148}, while at the same time boosting its effectiveness^{125, 148}.

Jiaogulan Slows Down Aging and Increases Longevity

Studies with aging animals have shown that Jiaogulan improves their memory and learning ability ¹⁵⁶, and rejuvenates their skin^{47, 48, 157}. It was also found that the herb increases the thickness of the skin, boosts synthesis of collagen, and protects elasticity¹⁵⁸. For extra skin benefit, you can also apply Jiaogulan tea topically, for example as a face rinse.

In another study, the lifespan of fruit flies was increased by as much as 50% when given Jiaogulan.¹⁶⁰ Other animal studies have also demonstrated increase in lifespan.^{161, 162}

Jiaogulan Prevents and Fights Diabetes Mellitus

Jiaogulan fights diabetes, as demonstrated in multiple clinical and animal studies:

• Jiaogulan Decreases Insulin Resistance
Gynostemma improves glucose tolerance by improving the cells’ ability to use insulin to absorb more glucose. ^{68, 163, 164, 165, 166, 167} It seems to achieve this, at least in part, by inhibiting the activity of an enzyme called protein tyrosine phosphatase (PTP1B), which plays a key role in insulin resistance. ^{^{168, 169, 170}}

• Jiaogulan Stimulates Insulin Production
Jiaogulan stimulates insulin release from the pancreas, so that more insulin is available to the body to help cells with absorbing glucose. ^{^{171, 172, 173}}

Jiaogulan Increases Blood Insulin Levels
Jiaogulan increases insulin concentrations in the blood by improving the liver’s capacity to metabolize glucose.^{^{165, 173, 174, 175}}

• Jiaogulan Lowers Blood Glucose Levels
Jiaogulan reduces blood glucose levels and inhibits increases in blood glucose after a glucose challenge test. ^{^{173, 174, 176}}

• Jiaogulan Protects From Diabetic Damage
Jiaogulan prevents damage to the cardiovascular system as a result of diabetes.^{99, 100}

In one human clinical study, patients were divided in a placebo and a Jiaogulan treatment group. The two groups did not differ in baseline characteristics and diabetic parameters, and all participants received the same diet and exercise therapies.

Four weeks of treatment were followed by two weeks of no treatment, after which the treatments were reversed so that the placebo-group was given Jiaogulan, and vice versa.

The study found that Gynostemma had the effect of lowering the fasting plasma glucose (FPG) level (the glucose concentration in the blood after at least 8 hours of fasting), while there was no change in the placebo group.Once the treatments were reversed, the former placebo group also showed lower glucose levels.

Meanwhile, the group that was initially treated with Jiaogulan showed lower glucose level during the entire 10-week duration of the trial compared to their levels before the start of the trial.

This happened despite the fact they only took Gynostemma for the first 4 weeks of the 10-week duration of the trial.¹⁶³

In another clinical study with type 2 diabetes patients, subjects were divided into two groups: one treated with sulfonylurea (an anti-diabetic drug) and Jiaogulan, and another with sulfonylurea and a placebo.

The researchers found that the group using Jiaogulan with sulfonylurea showed lower blood glucose levels and lower insulin resistance compared to the group that was administered sulfonylurea with placebo.

Furthermore, the effect of Jiaogulan and sulfonylurea was comparable to that of using sulfonylurea and metformin, another popular anti-diabetic drug.¹⁷⁷

Jiaogulan Protects and Boosts the Immune System

Jiaogulan’s beneficial effects on the immune system are mostly due to its antioxidant properties and ability to balance Nitric Oxide production.

Jiaogulan’s ability to reduce Nitric Oxide when the immune system is overactive is therefore vital in the prevention of inflammatory and autoimmune diseases, including some cancers, rheumatoid arthritis, gout, heart disease, periodontitis, and hay fever.

The herb also fights inflammation by decreasing free radical damage and inhibiting Nuclear Factor-kappaB (NF-kB) – a protein involved in cell survival and signaling – both important factors in the generation of inflammation.^{30, 32, 62, 93, 94, 178, 179, 180, 181}

As an antioxidant, the herb protects the integrity of the immune system from free radicals and environmental toxins ^{26, 30, 32}

Gynostemma also protects the immune system from the effects of stress ⁶, rigorous or exhaustive physical exercise ^{182, 183, 184}, and cancer chemotherapy and radiation therapy^{149, 150, 151, 152, 153, 154}.

Finally, Jiaogulan increases the potency of the immune response to foreign invaders, toxins,^{6, 30, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196} and cancer ^{118, 119, 138, 139, 186}.

Jiaogulan Protects and Strengthens the Nervous System

Nitric Oxide plays an important role in learning and memory by helping nerve cells in the brain to communicate with each other.^{197, 198} It is involved in neurotransmitter release, neural development and regeneration, synaptic plasticity and regulation of gene expression.¹⁹⁹

At normal concentrations, Nitric Oxide protects the nerve cells from damage and cell death. However, at high concentrations it becomes toxic to the nerve cells and can cause cell injury and cell death.²⁰⁰

Overproduction of Nitric Oxide in the nervous system has been linked to Alzheimer’s disease, Parkinson’s disease, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Huntington’s disease, and depression.²⁰¹

In addition, free radical damage has been shown to play a major role in the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.^{202, 203}

In light of this, it’s not surprising that Jiaogulan has been shown to help prevent both Alzheimer’s ^{204, 205, 206, 207} and Parkinson’s ^{37, 208, 209, 210, 211, 212}, which are the 6^th and 14^th leading causes of death in the United States respectively. It may also be effective against optic neuritis, although further studies are needed.²¹³

In both human and animal studies, Gynostemma was shown to improve brain functions like memory, concentration, and learning, especially with the elderly.^{156, 214, 215, 216}

The herb also helps protect against and recover from brain and memory damage induced by alcohol^{217, 218} and free radicals^{31, 34, 35, 36, 37, 38, 49}, as well as damage and cognitive impairment from ischemia-reperfusion and hypoxia due to stroke and other causes.^{34, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227}

A study with elderly cerebral infarction patients (a type of ischemic stroke) showed that administering Jiaogulan for a 12-week period improved their cognitive functions to a level close to that of normal elderly subjects who had not suffered a stroke. In addition, the improvements were better than that of a control group that was given Piracetam, a popular nootropic and brain-enhancing drug.²²⁸

A second clinical study using different evaluation methods showed identical results, and further improvement when treatment was continued for 12 more weeks (24 weeks in total).²²⁹

Jiaogulan can also prevent brain and nervous system damage caused by consumption of the popular flavor enhancing food additive Monosodium Glutamate (MSG).^{230, 231, 232, 233}

Lastly, the herb was found to increase the excitability and stability of the brain during athletic competition. A Guiyang Medical College research group carried out testing on more than 300 professional athletes, including athletes of the China National Skating Team.

All of the tested athletes reported that a Jiaogulan/Danshen recipe taken before the competition made them vigorous and alert, with quick reflexes and less nervousness. A control group taking Danshen alone did not feel increased stability and excitability of the nervous system during competition, although they also felt increased energy and endurance.^{234, 235}

Jiaogulan Improves Athletic Performance

Jiaogulan is able to increase athletic performance in several ways:

1. By regulating the production of Nitric Oxide.
2. By improving heart function efficiency.
3. By stimulating the production of the endogenous antioxidants glutathione and superoxide dismutase.

Since one of the main functions of Nitric Oxide is to widen the arteries (vasodilation), it has the effect of increasing blood circulation throughout the body. This provides more of the oxygen and glucose the muscles need to be able to work at peak levels longer, improving stamina and energy levels.

Nitric Oxide also stimulates growth hormone production²³⁶, which encourages fat reduction and muscle building.

Jiaogulan also improves the efficiency of the pumping action of the heart, so that it doesn’t work as hard to produce the same amount of blood flow. Again, more oxygen and nutrients reach the muscles and performance is improved.

A clinical study at the Guiyang Medical College with 30 normal healthy persons and 220 athletes showed that within 30 minutes after oral administration of a single dose of Jiaogulan combined with other Chinese medicinal herbs, all subjects responded with increased cardiac output and stroke volume, while heart rate and blood pressure did not change.²³⁷

Animal studies have confirmed this positive effect on heart function and have concluded that Jiaogulan’s effect is more potent than that of ginseng ^{103, 238}

A number of studies involving forced swimming tests with animals have proven that Jiaogulan has a significant anti-fatigue effect and increases the endurance capacity in animals, enabling them to swim significantly longer before they get exhausted. In addition, these effects become stronger as the dose is increased.^{239, 240, 241, 242, 243, 244, 245, 246}

Jiaogulan significantly increases glucose levels in the blood, liver and muscles, which is the fuel the muscles use and is therefore very important for the prolongation of endurance exercise.

Furthermore, Gynostemma decreases the amount of lactic acid (the build-up of which causes sore muscles the day after rigorous exercise) in the blood significantly and this is an important indicator for judging the degree of fatigue and means that Jiaogulan is able to postpone the appearance of fatigue and accelerate the recovery from fatigue.^{239, 240, 241, 242, 243, 244}

In parallel, the levels of uric nitrogen in the blood are decreased ^{241, 242, 243, 244, 245, 246}, which means that not as much protein needs to be digested in order to produce energy.

Jiaogulan also helps us reach peak mental and physical function by boosting the levels of the endogenous antioxidants superoxide dismutase (SOD) and glutathione, and lowering Malondialdehyde (MDA).^{241, 243, 244, 245, 246, 247, 248, 249, 250}

This means less muscle damage resulting from exercise, quicker recovery time, increased strength, endurance and a shift in the metabolism from fat production to muscle development.Finally, Gynostemma is able to regulate immune function during exercise, recovering immune indices to normal values from either originally lower or higher than the normal.^{182, 183, 184}

This is important because it has been demonstrated that the immune system is suppressed after rigorous exercise. Marathon runners and the high frequency of respiratory tract infections immediately after a run are one example.

If you are involved in physical exercise, act like the pros and have some Jiaogulan before a workout for extra energy and stamina, and after workout to help your body repair more quickly from the damage physical exercise inevitably causes.

Other Health Benefits of Jiaogulan

Anti-Anxiety and Anti-Stress

Being an adaptogen, Jiaogulan reduces mental and physical stress. It has also been shown to have a significant anxiolytic (anti-anxiety) effect and to help recover dopamine and serotonin levels back to normal.^{6, 211, 251, 252, 253, 254}

One double-blind placebo-controlled human clinical trial demonstrated the herb’s ability to significantly reduce anxiety and stress in groups of high anxiety and normal individuals by over 20% and 10% respectively, as evaluated by standard anxiety and stress tests.²⁵⁵
Jiaogulan has also shown promise in the treatment of depression.²⁵⁶
Promotes Weight Loss

Jiaogulan helps reduce weight in overweight people, at least in part by activating AMP-activated protein kinase (AMPK).^{257, 258} In addition, the herb’s ability to increase insulin sensitivity in the body also has beneficial weight-stabilizing or weight-loss effects.²⁵⁹

A 12-week, randomized, double blind, placebo-controlled clinical trial was done with 80 participants who were considered obese according to Asia-Pacific guidelines. 40 subjects were given an extract of one of Jiaogulan’s active ingredients and 40 were given placebo.

The subjects made no changes to their lifestyle. Body weight in the Jiaogulan group dropped by 1.35kg, fat mass dropped by 1.25kg, and waist circumference dropped by 2.62 centimeters on average. None of these changes were observed in the placebo group.²⁶⁰

A second randomized, single-blind, placebo-controlled clinical trial involving 56 subjects who were diagnosed with non-alcoholic fatty liver also found statistically significant effect of Jiaogulan extract on Body Mass Index (BMI), as well as improvements in other parameters over the placebo group.²⁶¹

Jiaogulan has also been reported to help those who are underweight to gain mass by improving metabolism and nutrient absorption. However, no studies have yet been done to test this claim.
Cleanses the Body From Toxins

Jiaogulan has been widely reported to protect and cleanse the body from toxins.^{294, 295, 296} The herb is able to do that by stimulating the production of the antioxidant glutathione, which plays a vital role in detoxifying the body by binding to pesticides, heavy metals and other toxins until they are excreted.
Protects the Liver
Jiaogulan was found to completely cure Hepatitis B in a 5.5 years long clinical trial with an effective rate of 77.5%.²⁶² In short-term clinical studies (3 months or less), Jiaogulan was also found to have positive effect on patients with a chronic hepatitis B infection.^{263, 264}Prevents liver fibrosis – a scarring process that represents the liver’s response to injury – which can lead to cirrhosis of the liver, liver failure and liver cancer.^{45, 265, 266, 267, 268, 269, 270}

Effective both as a stand-alone treatment for non-alcoholic fatty liver disease caused by high fat and cholesterol diet²⁷¹, and as an add-on treatment in a 6 month long human clinical study²⁶¹. Jiaogulan prevents liver fatty degeneration in fatty liver disease by modulating fat metabolism, ameliorating liver dysfunction, reducing oxidative stress²⁷², and protecting liver cells from injury and death⁶¹.

Protects against liver damage and cell death caused by ischemia/reperfusion via its antioxidant activity.²⁷³
Protects and Improves Kidney Function

Three separate clinical studies with hundreds of patients suffering from chronic renal failure showed that Jiaogulan can decrease blood fats and improve kidney function, anaemia, and the nutritional situation in these patients.^{274, 275, 276}

Protects the kidneys from damage due to toxins.²⁷⁷
Suppresses the development of renal fibrosis.^{278, 279}

Protects against kidney failure and gout by lowering blood uric acid in cases of hyperuricemia (abnormally high level of uric acid in the blood), which can cause both of these conditions.²⁸⁰
Fights Respiratory Issues and Supports the Lungs

Jiaogulan is effective against respiratory issues, such as cough, asthma, chronic bronchitis, and chronic tracheitis (inflammation of the trachea).^{191, 196, 281, 282, 283, 284}

In a clinical study of 86 patients with chronic bronchitis, Jiaogulan was found to effectively treat 93% of the cases.²⁸⁵

In another clinical study of 96 cases, Jiaogulan was effective 92% in treating chronic bronchitis.²⁸⁶

The herb is used traditionally as an expectorant and decongestant since it helps clear mucus from the airways, lungs, bronchia and trachea.¹⁹⁶
Protects the Gastro-Intestinal System

Jiaogulan protects the GIT from damage due to toxins²⁷⁷ and improves digestion and metabolism.

It protects against and heals gastric ulcers^{46, 287}, as well as chronic atrophic gastritis²⁸⁸.
It improves bowel movement function and alleviates constipation.

Helps regulate the gut microbiome ecosystem by increasing the number of symbiotic bacteria. This may in part contribute to the anticancer effect of Gynostemma, since the gut ecosystem can play an important role in diseases such as cancer, autism, rheumatoid arthritis, and allergies.²⁸⁹
Balances Hormonal Function

Jiaogulan normalizes and regulates the endocrine/hormonal system, especially adrenal function.^{2, 300}
Protects and Benefits the Reproductive System

Jiaogulan improves sexual function and helps with Erectile Dysfunction because it regulates Nitric Oxide production. Nitric Oxide plays a key role in developing and maintaining penile erection due to its ability to dilate the arteries and increase blood flow to the whole body, including the penis.^{209, 290, 291}

Increasing Nitric Oxide production is the biological basis of how the popular drug Viagra works.

Nitric Oxide is also important in sperm production and motility, ovarian function and ovulation, oviduct (the tube that links the ovary to the uterus) function, formation of the placenta, pregnancy, labour, sexual behaviour, and generation of steroid hormones.²⁹²
Jiaogulan has been shown to protect the sperm from damage due to toxins³⁹ and high blood fat content²⁹³.
Treats Insomnia

Gynostemma has been used as an effective treatment for insomnia in folk medicine, especially when it occurs because of excessive stress or anxiety. This is because it soothes the nerves and has anti-stress and anxiety effects on the body. A Guiyang Medical College study with 112 patients showed that Jiaogulan could improve sleep with an effective rate of 89 – 95%.²⁹⁷
Protects the Skin From Sun Damage

Jiaogulan has been shown to protect from UV radiation when applied directly to the skin.^{157, 298, 299} Even if consumed only as a tea, the herb will still have a protective effect against sunburn because it’s a powerful antioxidant. This is important in the prevention of melanoma (skin cancer) and premature aging of the skin.
Helps Against Psoriasis

Jiaogulan has shown promise in the treatment of Psoriasis, a chronic inflammatory skin disorder.³⁰¹
Anti-Viral, Anti-Fungal and Anti-Bacterial

Jiaogulan has been used for hundreds of years in folk medicine for the prevention of colds and the flu.

It has demonstrated strong anti-viral potential against Yellow Fever³⁰² and Polio³⁰³, diseases that have no known treatment drugs. It was also shown to have potent and selective anti-retroviral potential against the HIV-1 retrovirus, which is reported to cause AIDS.³⁰⁴
Jiaogulan inhibits growth in several types of fungi and bacteria.³⁰⁵
Headaches and Migraines

Jiaogulan has been shown to alleviate headaches and migraines.³⁰⁶
Hangover

If you ever find you’ve had a few too many drinks the night before, have a couple of cups of Jiaogulan tea in the morning – you’ll be pleasantly surprised!

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